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‘It was only a subject of selecting up a guide on mobile biology and beginning to study. I'd come from a globe of extremely-substantial vacuums, cryostats and quantum phenomena, and now I used to be Operating at home temperature with molecular biology kits.
Given that 2000, Dekker has shifted the leading concentrate of his operate to biophysics exactly where he experiments the properties of solitary biomolecules and cells utilizing the instruments of nanotechnology. This change of area was driven by his fascination for that extraordinary functioning of biological molecular constructions, and also via the long-phrase viewpoint that lots of appealing discoveries is usually expected With this industry.[five] Current lines of study in his biophysics group are within the areas of:[6]
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style in 2005. (nl)
Microbiology has only existed for a century, because we started to examine micro-organisms far more severely. I assumed nanobiology was an ideal time period, for the reason that all molecular Organic applicable interactions occur at the nanoscale: a protein is several nanometres in measurement, DNA is 2 nm thick.’
‘At the outset we checked out biological techniques which has a physical check out and acted on The premise of the resources we understood. It took a number ceesdekker.net of years prior to we started out Performing more on the big biological difficulties. I then began to connect with it nanobiology, a term that did not exist at time.
Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA in a very cooperative fashion
In 1993, for a young and eager associate professor at Delft College of Technological know-how, I had originally centered the investigate efforts of my group on measuring the electrical conductance of an individual conducting-polymer molecule. In just two years, we had designed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was connected amongst two intently spaced metallic nanoelectrodes.
There was 1 difficulty however — we didn't observe any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule stage, conducting polymers ended up basically not these types of great conductors, which was instead disappointing. We Therefore broadened our check out to try to locate much more promising molecules.
In 1993 he was appointed as Affiliate Professor at Delft College of Technology. Inside the mid-nineteen nineties Dekker and his team attained results with the invention from the electronic Houses of carbon nanotubes, the main single-molecule transistor along with other nanoscience.
Character Physics many thanks the anonymous reviewers for his or her contribution on the peer evaluation of the perform.
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2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes